C4b-binding protein binds to necrotic cells and DNA, limiting DNA release and inhibiting complement activation
نویسندگان
چکیده
منابع مشابه
C4b-binding protein binds to necrotic cells and DNA, limiting DNA release and inhibiting complement activation
After cell death, via apoptosis or necrosis, the uptake of dead cells by neighboring cells or phagocytes prevents the release of intracellular content. An array of molecules, including initiation molecules of the complement system, are involved in marking dead cells for uptake. After binding of these molecules, complement activation takes place, which when uncontrolled might result in a proinfl...
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ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 2005
ISSN: 1540-9538,0022-1007
DOI: 10.1084/jem.20050189